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eIF2Bδ blocks the integrated stress response and maintains eIF2B activity and cancer metastasis by overexpression in breast cancer stem cells.
Proc Natl Acad Sci U S A. 2023 Apr 11;120(15):e2207898120. doi: 10.1073/pnas.2207898120. Epub 2023 Apr 4.
Proc Natl Acad Sci U S A. 2023.
PMID: 37014850
Free PMC article.
Hyperactive mTOR and MNK1 phosphorylation of eIF4E confer tamoxifen resistance and estrogen independence through selective mRNA translation reprogramming.
Geter PA, Ernlund AW, Bakogianni S, Alard A, Arju R, Giashuddin S, Gadi A, Bromberg J, Schneider RJ.
Geter PA, et al.
Genes Dev. 2017 Nov 15;31(22):2235-2249. doi: 10.1101/gad.305631.117. Epub 2017 Dec 21.
Genes Dev. 2017.
PMID: 29269484
Free PMC article.
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